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SAVE THE DATE: HOPE 2020, January 29-31, Paris

The second edition of the "pHysiopathology of Parkinson's DisEase" (HOPE) conference, co-organized by NeurATRIS, will be held from 29 to 31 January 2020 at ICM in Paris.

Following the success of the first edition and the very stimulating feedback from participants regarding the latest scientific advances and the integration of basic research into clinical research, we are pleased to invite you to take part in this second edition.

The topics will cover the epigenetic and genetic determinants of Parkinson's disease, their molecular mechanisms and their modelling, in order to better understand the pathophysiology of Parkinson's disease and open pre-clinical, clinical and imaging perspectives.

In addition we propose a workshop the first day on two topics that will be discussed later on during the congress

1)      Cellular modelling using microfluidic and stem cell technologies

2)      Available imaging tools for cellular models and to humans

The definitive program and registrations will soon be available on the conference website: https://hope2020.sciencesconf.org/

A new target to treat spinocerebellar ataxia ?

Spinocerebellar ataxias are genetic neurodegenerative diseases of the cerebellum and brainstem causing numerous motor disorders, for which no curative or preventive therapies are available. SCA3 or Machado-Joseph disease (MJD) is the most prevalent ataxia worldwide. In their work published on June 14 in Acta Neuropathologica, Nathalie Cartier-Lacave, researcher from Inserm at the Brain and Spine Institute and NeurATRIS member, and her team have discovered the crucial role of an enzyme allowing to alleviate symptoms of the disease in mice.

Read the complete press release on the ICM website (in French): https://icm-institute.org/fr/actualite/nouvelle-cible-therapeutique-traiter-ataxies-spinocerebelleuses/

Scientific Publication:

RESTORING BRAIN CHOLESTEROL TURNOVER IMPROVES AUTOPHAGY AND HAS THERAPEUTIC POTENTIAL IN MOUSE MODELS OF SPINOCEREBELLAR ATAXIA.

Nóbrega C, Mendonça L, Marcelo A, Lamazière A, Tomé S, Despres G, Matos CA, Mechmet F, Langui D, den Dunnen W, de Almeida LP, Cartier N, Alves S.

Acta Neuropathol. 2019 Jun 14.

 

Multiple sclerosis: when the system gets carried away - France Culture

Two researchers members of NeurATRIS, Catherine Lubetzki and Bernard Zalc, talked about research and therapy progress on multiple sclerosis on Monday, June 17, 2019 on the radio France Culture (in French).

Read more...

NeurATRIS Webinars 2019 videos are online

The research infrastructures NeurATRIS and EATRIS offered on April 17 and May 6, 2019 two webinars dedicated to biological and technological tools for translational research on neurodegenerative diseases: in vivo preclinical models, jointly organized with the infrastructure Celphedia, and ultra high field MRI and MRS, jointly organized with the infrastructure France Life Imaging.

Watch the videos online: https://eatris.eu/solutions/transmedacademy/